8号三体的局限性胎盘嵌合体与宫内生长迟缓
Confined placental mosaicism for trisomy 8 and intra-uterine growth retardation.
作者信息
Saks E, Mccoy M C, Damron J, Kelly T E
机构信息
Division of Medical Genetics, University of Virginia Hospital, Charlottesville, USA.
出版信息
Prenat Diagn. 1998 Nov;18(11):1202-4. doi: 10.1002/(sici)1097-0223(199811)18:11<1202::aid-pd425>3.0.co;2-q.
This report describes a case of apparent confined placental mosaicism for trisomy 8 in a pregnancy which produced a male infant with intra-uterine growth retardation. Postnatal cytogenetic and molecular studies were consistent with biparental disomy 8. Postnatally, the infant experienced a period of rapid catch-up growth and exhibited no clinical features of trisomy 8 mosaicism. His development was age appropriate.
本报告描述了一例妊娠中出现的8号染色体三体局限型胎盘嵌合体病例，该妊娠产出一名患有宫内生长迟缓的男婴。产后细胞遗传学和分子研究结果与8号染色体双亲二体一致。产后，该婴儿经历了一段快速追赶生长的时期，且未表现出8号染色体三体嵌合体的临床特征。其发育与年龄相符。
Zotero 插件