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[蛛网膜下腔出血急性期脑血管痉挛时血管壁胶原弹性支架的超微结构变化]

[The ultrastructural changes in the collagenous-elastic skeleton of the wall of the cerebral vessels in spasm in the acute period of a subarachnoid hemorrhage].

作者信息

Krylov V V, Gusev A S, Titova G P, Gusev S A

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1998 Jul-Sep(3):10-5.

PMID:9854780
Abstract

Electron microscopic study of arteries in spasm and ischemia of the brain revealed substantial ultrastructural changes in the vascular wall. The changes are characterized by varying thickness, edema, dissociation of fibrillar and amorphous components of internal elastic membrane of the arterial wall, by lesion in the network of collagen fibers on its inner surface, by the presence of defibrotic and uncoiled collagenous fibers of the adventitia. The changes are followed by the impairment of the arterial skeleton and hence they lead to their altered elastic properties.

摘要

对大脑痉挛和缺血状态下动脉的电子显微镜研究显示,血管壁出现了大量超微结构变化。这些变化的特征在于动脉壁内弹性膜的厚度各异、水肿、纤维状和无定形成分解离,内表面胶原纤维网络受损,外膜存在去纤维化和未卷曲的胶原纤维。这些变化随后导致动脉骨架受损,进而使其弹性特性改变。

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