Sue T K, Jaques L B
Atherosclerosis. 1976 Oct;25(1):137-9. doi: 10.1016/0021-9150(76)90056-3.
Fifteen chicken tissues were examined for mast cells. Numerous mast cells were found in peritoneum and spleen. The sulfated mucopolysaccharides extracted from these two tissues, corresponding in amount to that in mast cells, were found to be dermatan sulfate, chondroitin sulfate and heparitin sulfate but no evidence of heparin. We have shown a similar situation occurs in the rabbit which is also highly susceptible to the production of atherosclerosis by diet. These observations provide further evidence of a role for heparin and mast cells in limiting atherogenesis.
对15份鸡组织进行了肥大细胞检测。在腹膜和脾脏中发现了大量肥大细胞。从这两种组织中提取的硫酸化粘多糖，其含量与肥大细胞中的相当，发现是硫酸皮肤素、硫酸软骨素和硫酸类肝素，但没有肝素的迹象。我们已经表明，在兔子身上也会出现类似情况，兔子也极易因饮食而产生动脉粥样硬化。这些观察结果进一步证明了肝素和肥大细胞在限制动脉粥样硬化形成中所起的作用。
