Kirsh M M, Rotman H, Bove E, Argenta L, Cimmino V, Tashian J, Ferguson P, Sloan H
Ann Thorac Surg. 1976 Oct;22(4):369-73. doi: 10.1016/s0003-4975(10)64969-7.
The results of major pulmonary resection in 58 patients greater than 70 years of age were reviewed. The histological distribution and extent of nodal metastases in this age group are the same as in younger patients. The absolute five-year survival rate for the 55 patients undergoing curative resection was 30% (17 patients). It was 36% (11 patients) for those patients with squamous cell carcinoma and 22% (5 patients) for those with adenocarcinoma. The operative mortality was only 14% (8 patients). Of the 49 patients treated by lobectomy, 17 lived five years or more free of disease, whereas none of the 6 patients treated by pneumonectomy survived five years. The five-year survival rate of 30% in this series of elderly patients treated by major pulmonary resection makes resections in such patients with bronchogenic carcinoma worthwhile.
对58例70岁以上患者进行肺大部切除术的结果进行了回顾。该年龄组的组织学分布和淋巴结转移范围与年轻患者相同。55例行根治性切除术患者的绝对五年生存率为30%(17例)。鳞状细胞癌患者为36%(11例),腺癌患者为22%(5例)。手术死亡率仅为14%(8例)。在49例行肺叶切除术的患者中,17例存活5年或更长时间且无疾病复发,而6例行全肺切除术的患者无一存活5年。在这组接受肺大部切除术治疗的老年患者中,五年生存率为30%,这表明对这类支气管癌患者进行手术切除是值得的。