Casset-Senon D, Philippe L, Babuty D, Eder V, Fauchier L, Fauchier J P, Pottier J M, Cosnay P
Nuclear Medicine Department, UMR CNR 6542, Trousseau Hospital, Tours, France.
Am J Cardiol. 1998 Dec 1;82(11):1399-404. doi: 10.1016/s0002-9149(98)00649-3.
To evaluate the diagnostic performance of Fourier phase analysis of gated blood pool single-photon emission computed tomography (GBP SPECT) in arrhythmogenic right ventricular (RV) cardiomyopathy, 18 patients with confirmed arrhythmogenic RV cardiomyopathy underwent GBP SPECT and x-ray cineangiography. Results were compared with data obtained with GBP SPECT in 10 control subjects. This 3-dimensional method demonstrated good correlation with cineangiography for measurements of RV enlargement and extent of the disease; RV and left ventricular segments were analyzed with the same accuracy. Tomographic abnormalities were significant decreased RV ejection fraction, RV dilatation, nonsynchronized contraction of the ventricles, increased RV contraction dispersion, presence of segmental RV wall motion disorders and/or phase delays, and occasionally regional left ventricular abnormalities. RV-delayed phase areas were always present in our population. A scoring system with RV criteria was proposed to diagnose RV disease. Because Fourier analysis of GBP SPECT provides ventricular morphologic information for the right ventricle with the same accuracy as for the left ventricle, it may replace planar radionuclide studies. Therefore, this method is helpful in patients with a strong clinical suspicion of arrhythmogenic RV cardiomyopathy, and should be used as a screening method before right ventriculography.
为评估门控心血池单光子发射计算机断层扫描（GBP SPECT）的傅里叶相位分析在致心律失常性右心室心肌病中的诊断性能，18例确诊为致心律失常性右心室心肌病的患者接受了GBP SPECT和X线电影血管造影检查。将结果与10名对照受试者GBP SPECT检查获得的数据进行比较。这种三维方法在测量右心室扩大和疾病范围方面与电影血管造影显示出良好的相关性；对右心室和左心室节段的分析具有相同的准确性。断层扫描异常表现为右心室射血分数显著降低、右心室扩张、心室不同步收缩、右心室收缩离散度增加、存在节段性右心室壁运动障碍和/或相位延迟，偶尔还会出现局部左心室异常。在我们的研究人群中总是存在右心室延迟相位区域。提出了一种基于右心室标准的评分系统来诊断右心室疾病。由于GBP SPECT的傅里叶分析可为右心室提供与左心室相同准确性的心室形态学信息，它可能会取代平面放射性核素研究。因此，该方法对临床高度怀疑致心律失常性右心室心肌病的患者有帮助，应在右心室造影前用作筛查方法。
