Kaczmarek W, Pucher A
Katedra i Klinika Ortopedii, Akademia Medyczna im. Karola Marcinkowskiego w Poznaniu.
Chir Narzadow Ruchu Ortop Pol. 1998;63(4):363-71.
Forty patients (27 males and 13 females) aged 18 months-41 years with preliminary diagnosis of osteoid osteoma localized within lower limb were reviewed. All underwent surgery. Histopathology confirmed previous diagnosis in 29 patients but in 11 cases (30%) histology either gave different diagnosis (despite clinical and radiological changes typical for osteoid osteoma) or was inconclusive. Three types of radiographic picture were distinguished: within cancellous bone the change was either osteolytic or oval, sclerotic; within cortical bone it was spindle-shaped, sclerotic. In 5 cases radiological symptoms were present prior to the pain. In 3 cases observed several years before surgery natural growth of osteoid osteoma could be traced. The key role of prostaglandin synthesized by osteoid osteoma in its pathology was emphasized.
回顾了40例初步诊断为下肢骨样骨瘤的患者（27例男性，13例女性），年龄在18个月至41岁之间。所有患者均接受了手术。组织病理学证实29例患者之前的诊断，但11例（30%）组织学结果要么给出了不同的诊断（尽管有骨样骨瘤典型的临床和放射学改变），要么无法得出结论。区分出三种放射影像学表现：在松质骨内，改变要么是溶骨性的，要么是椭圆形、硬化性的；在皮质骨内，表现为纺锤形、硬化性。5例患者在疼痛出现之前就有放射学症状。3例在手术前数年观察到骨样骨瘤的自然生长情况。强调了骨样骨瘤合成的前列腺素在其病理过程中的关键作用。
