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局灶性手部肌张力障碍中体感皮层数字表征的改变。

Alteration of digital representations in somatosensory cortex in focal hand dystonia.

作者信息

Elbert T, Candia V, Altenmüller E, Rau H, Sterr A, Rockstroh B, Pantev C, Taub E

机构信息

Department of Psychology, University of Konstanz, Germany.

出版信息

Neuroreport. 1998 Nov 16;9(16):3571-5. doi: 10.1097/00001756-199811160-00006.

DOI:10.1097/00001756-199811160-00006
PMID:9858362
Abstract

Focal hand dystonia involves a loss of motor control of one or more digits; it is associated with the repetitive, synchronous movements of the digits made by musicians over periods of many years. Magnetic source imaging revealed that there is a smaller distance (fusion) between the representations of the digits in somatosensory cortex for the affected hand of dystonic musicians than for the hands of non-musician control subjects. The data suggest that use-dependent susceptibility to digital representation fusion in cortex may be involved in the etiology of focal dystonia. A successful therapy for the condition has been developed based on this consideration.

摘要

局灶性手部肌张力障碍涉及一个或多个手指的运动控制丧失;它与音乐家多年来重复、同步的手指运动有关。磁源成像显示,肌张力障碍音乐家患侧手在体感皮层中手指表征之间的距离(融合)比非音乐家对照受试者的手更小。数据表明,皮层中数字表征融合的使用依赖性易感性可能参与了局灶性肌张力障碍的病因。基于这一考虑,已经开发出一种针对该病症的成功疗法。

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