Körfer R, Kleikamp G
Klinik für Thorax- und Kardiovaskularchirurgie, Herzzentrum Nordrhein-Westfalen, Bad Oeynhausen.
Herz. 1998 Nov;23(7):448-52. doi: 10.1007/BF03043406.
The ideal heart valve prosthesis has not been developed. The today available mechanical and biological prostheses are far from perfect concerning thrombogenesis, mechanical durability and hemodynamic performance. Failure of an implanted valve is possible due to inadequate indication, inadequate surgical technique and inadequate medical follow-up. The patient with a heart valve prosthesis must be seen as a life-long challenge for the cooperation between cardiologists and cardiac surgeons. This article describes the main causes of prosthetic heart valve dysfunction and the surgical treatment, including structural dysfunction, thrombosis, paravalvular leakage, tissue ingrowth and prosthetic valve endocarditis.
理想的心脏瓣膜假体尚未研发出来。就血栓形成、机械耐久性和血流动力学性能而言,目前可用的机械和生物假体远非完美。由于适应症选择不当、手术技术欠佳以及医疗随访不足,植入瓣膜可能会出现故障。心脏瓣膜假体患者必须被视为心脏病专家和心脏外科医生合作面临的一项终身挑战。本文介绍了人工心脏瓣膜功能障碍的主要原因及外科治疗方法,包括结构功能障碍、血栓形成、瓣周漏、组织长入和人工瓣膜心内膜炎。