LeDoux J
Center for Neural Science, New York University, NY 10003, USA.
Biol Psychiatry. 1998 Dec 15;44(12):1229-38. doi: 10.1016/s0006-3223(98)00282-0.
In recent years, there has been an explosion of interest in the neural basis of emotion. Much of this enthusiasm has been triggered by studies of the amygdala and its contribution to fear. This work has shown that the amygdala detects and organizes responses to natural dangers (like predators) and learns about novel threats and the stimuli that predict their occurrence. The latter process has been studied extensively using a procedure called classical fear conditioning. This article surveys the progress that has been made in understanding the neural basis of fear and its implications for anxiety disorders, as well as the gaps in our knowledge.
近年来，人们对情绪的神经基础产生了极大的兴趣。这种热情很大程度上是由对杏仁核及其在恐惧中所起作用的研究引发的。这项研究表明，杏仁核能够检测并组织对自然危险（如捕食者）的反应，并了解新出现的威胁以及预测其发生的刺激因素。后一过程已通过一种称为经典恐惧条件作用的程序得到广泛研究。本文综述了在理解恐惧的神经基础及其对焦虑症的影响方面所取得的进展，以及我们知识上的空白。
