两性霉素B胶体分散液治疗鼻窦眶曲霉病

Therapy of sinuorbital aspergillosis with amphotericin B colloidal dispersion.

作者信息

Rieske K, Handrick W, Müller H, Sterker I

机构信息

Department of Pediatrics, University of Leipzig, Germany.

出版信息

Mycoses. 1998 Sep-Oct;41(7-8):287-92. doi: 10.1111/j.1439-0507.1998.tb00340.x.

DOI:10.1111/j.1439-0507.1998.tb00340.x

PMID:9861833

Abstract

Invasive aspergillosis is a feared complication in the management of patients with malignancies. We report a 13-year-old boy with acute myelogenous leukaemia and chronic sinusitis who developed a sinuorbital fungal infection during cytostatic and prolonged antibiotic treatment. The clinical findings, diagnostic measures and treatment and its adverse effects are described and discussed. Special emphasis is given to our experience of the use of colloidal dispersed amphotericin B (Amphocil).

摘要

侵袭性曲霉病是恶性肿瘤患者治疗过程中令人担忧的并发症。我们报告一名13岁患有急性髓性白血病和慢性鼻窦炎的男孩，在进行细胞毒性药物治疗和长期抗生素治疗期间发生了鼻窦眼眶真菌感染。本文描述并讨论了其临床发现、诊断措施、治疗方法及其不良反应。特别强调了我们使用胶体分散两性霉素B（安浮特克）的经验。