[Facilitation of the effects of L-DOPA by alpha-methyldopa].
作者信息
Uspenskiĭ A E, Korobov N V
出版信息
Biull Eksp Biol Med. 1976 Mar;81(3):314-6.
PMID:986203
Abstract
Alpha-methyl-DOPA increased the duration of excitation induced by L-DOPA in mice, alpha-methyl-DOPA potentiated the anticataleptogenic activity of L-DOPA in mice pretreated with reserpine or haloperidol. Alpha-methyl-DOPA given to cats 30 min prior to L-DOPA diminished the influence of L-DOPA on the blood pressure and the contraction of the nictitating membrane. When given 4 to 6 hours prior to L-DOPA alpha-methyl DOPA enhanced the reaction of the blood pressure and contraction of the nictitating membrane induced by L-DOPA or dopamine.
摘要
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