Lamperti A, Niewenhuis R
Cell Tissue Res. 1976 Jul 30;170(3):315-24. doi: 10.1007/BF00219414.
The neurons of the arcuate nucleus were studied ultrastructurally in female hamsters that were given saline or 1 mg mercuric chloride/day during one estrous cycle. Membranous whorls, composed of 4-26 concentric layers of smooth endoplasmic reticulum, were found in 7-8% of the neurons of control animals in diestrus (D3) and in proestrus (D3) and in proestrus (D4). Whorls were found in 5-16% of the neurons in mercury-treated animals on all days of the experimental period. The whorls appeared to be associated with RER and Golgi bodies. The levels of FSH and LH were measured in the plasma and pituitaries of both groups of animals. There was a significantly higher concentration of FSH in the pituitaries of experimental animals on D3 and of LH on D1C2 of the subsequent cycle; plasma levels of FSH and LH were similar in both groups throughout the experimental period. The relationship between the levels of gonadotropins and the presence of membranous whorls is discussed.
在一个发情周期内，对每天给予生理盐水或1毫克氯化汞的雌性仓鼠的弓状核神经元进行了超微结构研究。在间情期（D3）和发情前期（D3）以及发情前期（D4）的对照动物的7-8%的神经元中发现了由4-26层同心的光滑内质网组成的膜性涡旋。在实验期的所有天数里，在汞处理动物的5-16%的神经元中发现了涡旋。这些涡旋似乎与粗面内质网和高尔基体有关。测量了两组动物血浆和垂体中促卵泡激素（FSH）和促黄体生成素（LH）的水平。在随后周期的D3，实验动物垂体中FSH的浓度显著更高，在D1C2时LH的浓度显著更高；在整个实验期，两组动物血浆中FSH和LH的水平相似。讨论了促性腺激素水平与膜性涡旋存在之间的关系。
