Ma Q, Li D, Zhong Y
Institute of Occupational Health, Chinese Academy of Preventive Medicine, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1997 Nov;31(6):355-7.
Sixty new employees in a cotton textile mill were followed up for five years to study their occurrence of byssinosis and its natural history. Results showed that the workers complained more cough, expectoration and other respiratory irritation symptoms at their early exposure to cotton dust, and the frequency of chest tightness in them reached the peak one year after exposure and remained at higher level later. Stratified analysis showed that all the respiratory symptoms did not correlate with their smoking habits, specific body constitution, etc. Forced expiratory volume at one second (FEV1) after shift declined with length of exposure and appeared a tendency to exacerbate gradually, especially in workers with a positive skin test of cotton antigen. Smoking had no influence on it. It suggests that exposure to cotton dust and idiosyncracy of the workers play important roles in damage to lung function.
对一家棉纺织厂的60名新员工进行了为期五年的随访，以研究棉尘肺的发病情况及其自然病程。结果显示，工人在早期接触棉尘时咳嗽、咳痰及其他呼吸道刺激症状较多，胸闷症状在接触后1年达到高峰，随后维持在较高水平。分层分析显示，所有呼吸道症状与吸烟习惯、特殊体质等均无关联。下班后第一秒用力呼气量（FEV1）随接触时间延长而下降，并呈逐渐加重趋势，尤其是棉尘抗原皮肤试验阳性的工人。吸烟对此无影响。这表明接触棉尘和工人的个体特质在肺功能损害中起重要作用。
