Kwon S J, Lee C W
Department of Dermatology, Hanyang University College of Medicine, Seoul, South Korea.
J Dermatol. 1998 Nov;25(11):756-8. doi: 10.1111/j.1346-8138.1998.tb02497.x.
A 23-year-old man had recurrent erythematous purpuric patches in a transverse-linear arrangement on his back and arms. One week prior to a recent episode, he took acetaminophen for 3 days. Four months earlier, he developed the same purpuric lesions at/around the same anatomical site when he took acetaminophen for pain-relief. A biopsy specimen showed capillaritis and extravasation of erythrocytes in the papillary dermis. A provocation test with acetaminophen confirmed these lesions as drug-induced rashes. The uncommon topographic and morphologic features of the purpuric lesion in this patient might be considered as an unusual expression of pigmented purpuric dermatosis caused by acetaminophen.
一名23岁男性的背部和手臂出现呈横向线性排列的反复性红斑紫癜斑。在最近一次发作前一周，他服用对乙酰氨基酚3天。四个月前，他在服用对乙酰氨基酚止痛时，在相同解剖部位/周围出现了相同的紫癜性病变。活检标本显示毛细血管炎和红细胞在乳头真皮层外渗。对乙酰氨基酚激发试验证实这些病变为药物性皮疹。该患者紫癜性病变不常见的部位和形态特征可能被视为由对乙酰氨基酚引起的色素性紫癜性皮病的一种不寻常表现。
