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[雌性小鼠性成熟速率的遗传分析]

[Genetic analysis of the rate of sexual maturation in female mice].

作者信息

Shiuler L, Borodin P M

出版信息

Genetika. 1976;12(4):41-6.

PMID:986339
Abstract

In studies of the female progeny of complete diallel crossing of BALB/c, C3H/He, C57BL/6, AKR/J mice a considerable influence of the genotype on the variability for such characters as the age of the vagina opening and the weight at that time, the age of the first oestrus and the weight at that time, the weight at 6 weeks was observed. The analysis of the effects of the general and specific combining ability demonstrated that non-additive gene effects play the major role in the determination of the day the begining oestral activity and the weight on this day. The age and the weight on the day of vaginal opening are inherited additively. It is demonstrated that the females of BALB/c and C3H/He (mammary tumour susceptible strains) are characterized by higher rate of sexual maturation than those of C57BL/6 and AKR/J in which the tumours of this localization are rare.

摘要

在对BALB/c、C3H/He、C57BL/6、AKR/J小鼠进行完全双列杂交的雌性后代研究中,观察到基因型对诸如阴道开口年龄及当时体重、首次发情年龄及当时体重、6周龄体重等性状的变异性有相当大的影响。对一般配合力和特殊配合力效应的分析表明,非加性基因效应在决定发情活动开始日及该日体重方面起主要作用。阴道开口日的年龄和体重呈加性遗传。结果表明,BALB/c和C3H/He(乳腺肿瘤易感品系)的雌性小鼠性成熟率高于C57BL/6和AKR/J的雌性小鼠,而后两种品系中该部位肿瘤很少见。

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