Newshan G, Taylor B, Gold R
St Vincent's Hospital, Section of HIV Medicine, New York, NY, USA.
Int J STD AIDS. 1998 Nov;9(11):672-6. doi: 10.1258/0956462981921332.
Sexual functioning is often neglected in the care of HIV-infected patients. Little information exists about the relationship between hormonal factors, psychological factors, medication, HIV disease stage and sexual functioning among persons with HIV disease. In this study, 50 HIV+ men completed the Derogatis Sexual Functioning Inventory (DSFI), and had serum hormonal assays drawn (testosterone, thyroid function test, leuteinizing hormone, prolactin and oestradiol). Although all the subjects reported some degree of sexual dysfunction, persons with symptomatic HIV/AIDS reported more negative mood, lower sexual satisfaction scores and worse body image than persons with asymptomatic HIV. Persons with asymptomatic HIV also tended to have normal testosterone levels compared with persons with symptomatic HIV/AIDS. No relationship was found between medications and low testosterone, although numbers were small. These results suggest that sexual dysfunction is prevalent among persons with HIV disease, is more common as patients become symptomatic and progress to AIDS and that both physiological (low testosterone) and psychological issues play a role.
在对感染艾滋病毒患者的护理中，性功能问题常常被忽视。关于艾滋病毒感染者体内激素因素、心理因素、药物治疗、艾滋病毒疾病阶段与性功能之间的关系，目前所知甚少。在本研究中，50名艾滋病毒呈阳性的男性完成了德罗加蒂斯性功能量表（DSFI）测试，并进行了血清激素检测（睾酮、甲状腺功能测试、促黄体生成素、催乳素和雌二醇）。尽管所有受试者均报告有一定程度的性功能障碍，但有症状的艾滋病毒/艾滋病患者比无症状的艾滋病毒感染者报告有更多负面情绪、更低的性满意度得分和更差的身体形象。与有症状的艾滋病毒/艾滋病患者相比，无症状的艾滋病毒感染者的睾酮水平往往正常。尽管样本数量较少，但未发现药物治疗与低睾酮水平之间存在关联。这些结果表明，性功能障碍在艾滋病毒感染者中普遍存在，随着患者出现症状并发展为艾滋病，性功能障碍更为常见，而且生理因素（低睾酮水平）和心理问题都发挥了作用。
