Kabbaj K, Baala L, Chhoul H, Sefiani A
Service de Pédodontie, CCTD, CHU, Rabat, Morocco.
J Med Genet. 1998 Dec;35(12):1043-4. doi: 10.1136/jmg.35.12.1043.
We studied a large Moroccan family in which anhidrotic ectodermal dysplasia is transmitted as an autosomal recessive trait. Fourteen family members, both males and females, were affected and they all had a common ancestor. Linkage analysis by homozygosity mapping in this family will permit the gene localisation of this rare form of anhidrotic ectodermal dysplasia.
我们研究了一个摩洛哥大家族，其中无汗性外胚层发育不良作为常染色体隐性性状遗传。家族中的14名成员，无论男女，均受此影响，他们都有一个共同的祖先。通过对该家族进行纯合性定位连锁分析，将能够确定这种罕见的无汗性外胚层发育不良的基因定位。
