用甲醛灭活的远缘链球菌细胞进行扁桃体给药可减少家兔的实验性龋齿。
Tonsillar application of formalin-killed cells of Streptococcus sobrinus reduces experimental dental caries in rabbits.
作者信息
Fukuizumi T, Inoue H, Tsujisawa T, Uchiyama C
机构信息
Department of Oral Bacteriology, Kyushu Dental College, Kitakyushu, Japan.
出版信息
Infect Immun. 1999 Jan;67(1):426-8. doi: 10.1128/IAI.67.1.426-428.1999.
Abstract
Living Streptococcus sobrinus cells were orally inoculated into nonimmune rabbits and rabbits immunized with formalin-killed cells of S. sobrinus through tonsillar application to examine the anticaries potential of this method of immunization. The living S. sobrinus cell numbers and the caries areas in the rabbits immunized by tonsillar application decreased to a level one-fifth of that in nonimmune rabbits.
摘要
将活的远缘链球菌细胞经口接种到未免疫的兔子以及通过扁桃体给药免疫了经福尔马林灭活的远缘链球菌细胞的兔子体内，以检测这种免疫方法的防龋潜力。经扁桃体给药免疫的兔子体内的活远缘链球菌细胞数量和龋损面积降至未免疫兔子的五分之一水平。
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