Nonrestricted differential intoxication of cells by pertussis toxin.
作者信息
el Bayâ A, Brückener K, Schmidt M A
机构信息
Institut für Infektiologie - Zentrum für Molekularbiologie der Entzündung, Westfälische Wilhelms-Universität Münster, Germany.
出版信息
Infect Immun. 1999 Jan;67(1):433-5. doi: 10.1128/IAI.67.1.433-435.1999.
Abstract
After uptake and retrograde transport pertussis toxin acts by ADP-ribosylating alpha-Gi proteins. We show that uptake via many different receptor proteins followed by retrograde transport and intoxication is not restricted to a particular cell type. The efficiency of cellular intoxication, however, was found to be cell type dependent.
摘要
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