van der Lely N, Vreede W B
Emma Kinderziekenhuis/Academisch Medisch Centrum, afd. Intensive Care Kinderen, Amsterdam.
Ned Tijdschr Geneeskd. 1998 Oct 17;142(42):2294-7.
Drowning and near-drowning are major causes of death and neurological damage, respectively, in children. The pathophysiological substrate consists of hypoxia, ischaemia, respiratory and metabolic acidosis and sometimes, hypothermia. Most cases involve aspiration of liquid; this leads to a persistent impairment of the gas exchange. Occurrence of arrhythmias and hypovolaemia is very likely. The main objective of treatment of the near-drowned is limiting cerebral damage. Treatment consists of resuscitation and stabilization, administration of oxygen with positive end-expiratory pressure, intravenous administration of liquids and central reheating. The prognosis depends in the first place on the duration of the submersion, which, however, is often difficult to establish. Submersion for over 5 minutes is prognostically unfavourable. In hypothermia due to submersion in ice cold water the prognostic factors are less clear--in these cases the treatment should always be continued until the core temperature is > or = 32 degrees C.
溺水和近乎溺水分别是儿童死亡和神经损伤的主要原因。病理生理基础包括缺氧、缺血、呼吸性和代谢性酸中毒,有时还包括体温过低。大多数病例涉及液体吸入;这会导致气体交换持续受损。心律失常和低血容量很可能发生。近乎溺水者治疗的主要目标是限制脑损伤。治疗包括复苏与稳定病情、呼气末正压给氧、静脉补液以及中心复温。预后首先取决于淹没时间,但这往往难以确定。淹没超过5分钟预后不佳。因淹没于冰冷水中导致体温过低时,预后因素不太明确——在这些情况下,治疗应持续至核心体温≥32摄氏度。