Shmyreva V F, Shershnev V V, Mazurova Iu V
Vestn Oftalmol. 1998 Sep-Oct;114(5):7-10.
The efficacy of surgical treatment of low (normal)-pressure glaucoma is validated on the basis of analysis of the disease progress risk factors. The risk factors are inadequate intraocular pressure (IOP) and insufficient blood supply to the optic nerve and retina. For stabilizing the glaucomatous process, IOP is to be reduced below 14 mm Hg. After antiglaucoma surgery, IOP decreases by 35% on average (to 13.9 mm Hg), and visual field is retained in remote period in 81.2% patients. Antiglaucoma operation with simultaneous decompression of the optic nerve results in a greater increase of visual field due to improvement of blood supply to the optic nerve and retina; visual functions are stabilized for a long time in 77.8% cases at a higher IOP (16.14 mm Hg) in patients with worse initial status. Functional results of surgery for normotensive glaucoma depend on ophthalmic tone and optic nerve and retinal hemodynamics.
基于对疾病进展风险因素的分析,证实了手术治疗低(正常)眼压性青光眼的疗效。这些风险因素包括眼压(IOP)不足以及视神经和视网膜的血液供应不足。为稳定青光眼病情,需将眼压降低至14毫米汞柱以下。抗青光眼手术后,眼压平均降低35%(至13.9毫米汞柱),81.2%的患者在远期可保留视野。同时对视神经进行减压的抗青光眼手术,由于改善了视神经和视网膜的血液供应,可使视野有更大程度的改善;在初始状态较差的患者中,77.8%的病例在较高眼压(16.14毫米汞柱)下,视觉功能可长期稳定。正常眼压性青光眼手术的功能结果取决于眼内压以及视神经和视网膜的血流动力学。