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Deletion of donor-reactive cells followed by stem cell transplantation in recipients treated with total lymphoid-irradiation as a means for induction of transplantation tolerance to organ allografts and xenografts.

作者信息

Slavin S, Gurevitch O, Zhu J, Prighozina T

机构信息

Department of Bone Marrow Transplantation, Hadassah University Hospital, Jerusalem, Israel.

出版信息

Transplant Proc. 1998 Dec;30(8):4021-2. doi: 10.1016/s0041-1345(98)01326-8.

DOI:10.1016/s0041-1345(98)01326-8
PMID:9865283
Abstract
摘要

相似文献

1
Deletion of donor-reactive cells followed by stem cell transplantation in recipients treated with total lymphoid-irradiation as a means for induction of transplantation tolerance to organ allografts and xenografts.在接受全身淋巴照射的受体中,先清除供体反应性细胞,然后进行干细胞移植,以此作为诱导对器官同种异体移植和异种移植产生移植耐受的一种手段。
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2
Permanent and specific transplantation tolerance induced by a nonmyeloablative treatment to a wide variety of allogeneic tissues: I. Induction of tolerance by a short course of total lymphoid irradiation and selective elimination of the donor-specific host lymphocytes.通过非清髓性治疗诱导对多种同种异体组织的永久性和特异性移植耐受:I. 通过短期全身淋巴照射和选择性清除供体特异性宿主淋巴细胞诱导耐受
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The combined use of sublethal irradiation and costimulatory blockade to generate mixed bone marrow chimeras.亚致死剂量照射与共刺激阻断联合使用以产生混合骨髓嵌合体。
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Immunohematopoietic reconstitution by allogeneic and autologous bone marrow grafts as a means for induction of specific unresponsiveness to donor-specific allografts and modified self in autoimmune disorders.
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Lack of pluripotent stem cell engraftment in cyclophosphamide-induced tolerance.环磷酰胺诱导的耐受性中多能干细胞植入的缺乏。
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7
Induction of stable long-term mixed hematopoietic chimerism following nonmyeloablative conditioning with T cell-depleting antibodies, cyclophosphamide, and thymic irradiation leads to donor-specific in vitro and in vivo tolerance.使用去除T细胞的抗体、环磷酰胺和胸腺照射进行非清髓性预处理后诱导稳定的长期混合造血嵌合状态,可导致供体特异性的体外和体内耐受。
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Induction of Major Histocompatibility Complex-mismatched Mouse Lung Allograft Acceptance With Combined Donor Bone Marrow: Lung Transplant Using a 12-Hour Nonmyeloablative Conditioning Regimen.采用联合供体骨髓诱导主要组织相容性复合体不匹配小鼠肺同种异体移植的接受:使用12小时非清髓性预处理方案的肺移植
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9
Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation.额外的单克隆抗体(mAB)注射可以替代胸腺照射,从而在经抗T细胞mAB和3戈瑞全身照射预处理后接受骨髓移植的小鼠中诱导混合嵌合体形成和耐受。
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10
Mixed allogeneic chimerism in the rat. Donor-specific transplantation tolerance without chronic rejection for primarily vascularized cardiac allografts.大鼠中的混合异基因嵌合体。主要血管化心脏同种异体移植物的供体特异性移植耐受且无慢性排斥反应。
Transplantation. 1995 Nov 15;60(9):971-80.