Combination therapy of malononitrilamides and tacrolimus (FK 506) induced long-term xenograft survival.
作者信息
Schorlemmer H U, Kurrle R
机构信息
Research Laboratories Hoechst Marion Roussel Deutschland GmbH, Wiesbaden, Germany.
出版信息
Transplant Proc. 1998 Dec;30(8):4170-3. doi: 10.1016/s0041-1345(98)01382-7.
PMID:9865337
Abstract
摘要
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1
Combination therapy of malononitrilamides and tacrolimus (FK 506) induced long-term xenograft survival.丙二腈酰胺与他克莫司（FK 506）联合治疗可诱导长期异种移植存活。
Transplant Proc. 1998 Dec;30(8):4170-3. doi: 10.1016/s0041-1345(98)01382-7.
2
Long-term allograft survival and tolerance induction by the synergistic activity of malononitrilamides and tacrolimus.丙二腈酰胺与他克莫司的协同活性实现长期同种异体移植存活及诱导免疫耐受
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3
Coadministration of malononitrilamides and tacrolimus induces tolerance in a rat skin allograft model.丙二腈酰胺与他克莫司联合给药可在大鼠皮肤同种异体移植模型中诱导耐受性。
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4
Long-term xenograft survival by combination therapy of malononitrilamide MNA 715 with cyclosporine.
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5
Control of mouse-to-rat skin xenograft rejection by malononitrilamides.丙二腈酰胺对小鼠-大鼠皮肤异种移植排斥反应的控制
Transplant Proc. 1996 Dec;28(6):3037-9.
6
Malononitrilamides reduce IgM and IgG xenoantibodies and prolong skin xenograft survival in a mouse-to rat model.丙二腈酰胺可降低小鼠至大鼠模型中的IgM和IgG异种抗体，并延长皮肤异种移植的存活时间。
Transplant Proc. 1998 Jun;30(4):976-9. doi: 10.1016/s0041-1345(98)00116-x.
7
Acute skin graft rejection can be prevented and treated in rat models by malononitrilamides.在大鼠模型中，丙二腈酰胺可预防和治疗急性皮肤移植排斥反应。
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8
Immunomodulatory activity of malononitrilamides, derivatives of leflunomide's primary metabolite, on models of experimental rheumatoid arthritis.来氟米特主要代谢物的衍生物丙二腈酰胺对实验性类风湿关节炎模型的免疫调节活性
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Malononitrilamides prevent the generation of oxygen radicals in mononuclear phagocytes and graft rejection in a rat model.丙二腈酰胺可防止大鼠模型中单核吞噬细胞产生氧自由基并抑制移植排斥反应。
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Prolongation of xenograft survival by combining donor-specific intravenous presensitization with FK 506.通过将供体特异性静脉预致敏与FK 506联合使用延长异种移植物存活时间。
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