Fox J M, Neumcke B, Nonner W, Stämpfli R
Pflugers Arch. 1976 Jul 30;364(2):143-5. doi: 10.1007/BF00585182.
The effect of ultraviolet radiation on the asymmetrical displacement currents in the membrane of the node of Ranvier was measured and compared with the ultraviolet blocking of the sodium current. Ultraviolet radiation irreversibly reduced the peak sodium current and the charge displaced during a depolarizing test pulse, the relative reduction being independent of potential. The ratio of the ultraviolet sensitivities of the sodium and the asymmetrical displacement currents is 2.3+/- 0.2. This result suggests two independent identical gating particles per sodium channel in the membrane of myelinated nerve.
测量了紫外线辐射对郎飞结膜中不对称位移电流的影响，并将其与钠电流的紫外线阻断作用进行了比较。紫外线辐射不可逆地降低了去极化测试脉冲期间的峰值钠电流和电荷位移，相对降低与电位无关。钠电流和不对称位移电流的紫外线敏感性之比为2.3±0.2。这一结果表明，在有髓神经膜的每个钠通道中有两个独立的相同门控粒子。
