Salvati M, Cervoni L, Puzzilli F, Raguso M, Ciappetta P, Delfini R
Neurological Mediterranean Neuromed Institute IRCCS, Pozzilli, Isernia.
Minerva Chir. 1998 Sep;53(9):727-30.
Metastatic compression of the spinal cord is a frequent occurrence throughout the evolution of neoplastic disease. Possible clinical-diagnostic strategies and therapeutic management of this pathology are discussed in terms of survival and quality of life.
The study includes 59 patients (40 males and 19 females, with an average age of 48.4 years) with metastatic spinal compression treated surgically in our centre (in some cases with stabilization of the spinal segment involved).
In 40 cases the localization of the primary tumor was known when the patient was admitted. The segment involved was the dorsal one in 41 cases. The most frequent type of tumor was pulmonary carcinoma in males and breast carcinoma in females. Average survival was 5.3 months. Treatment integrated by stabilization improved the quality of life in comparison to laminectomy alone. Survival was also influenced by the histological type and site of the primary tumor.
Surgical treatment not only prolongs survival but, above-all, guarantees a satisfactory quality of life.
在肿瘤疾病的发展过程中,脊髓转移瘤压迫是一种常见现象。本文从生存和生活质量方面探讨了这种病理状况可能的临床诊断策略及治疗管理。
该研究纳入了59例在我们中心接受手术治疗(部分病例还对受累脊髓节段进行了固定)的脊髓转移瘤压迫患者(40例男性和19例女性,平均年龄48.4岁)。
40例患者入院时已知原发肿瘤的部位。41例患者受累节段为胸段。最常见的肿瘤类型在男性为肺癌,在女性为乳腺癌。平均生存期为5.3个月。与单纯椎板切除术相比,联合固定治疗可改善生活质量。生存期还受原发肿瘤的组织学类型和部位影响。
手术治疗不仅能延长生存期,更重要的是能保证令人满意的生活质量。