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根据我们的个人经验对结直肠癌随访计划进行了修改。

Colorectal follow-up planning modified on the basis of our personal experience.

作者信息

Li Destri G, Rinzivillo C, Craxi G, La Greca G, Di Cataldo A, Puleo S, Licata A

机构信息

Fist Surgical Clinic, University of Catania, Italy.

出版信息

Dig Surg. 1998;15(1):64-8. doi: 10.1159/000018589.

Abstract

BACKGROUND

The authors, evaluating the disappointing follow-up results in patients suffering from colorectal carcinoma who had undergone surgery for cure, tried a more rational follow-up.

METHODS

In a retrospective review about 232 patients who adhered to the follow-up protocol, we evaluated the accuracy rates of CEA, liver ultrasonography and abdominal CT. In the same group of patients. we evaluated the type of correlation between the neoplastic recurrence rate and Astler-Coller's classification.

RESULTS

(1) In detecting hepatic metastases CEA levels furnished sensitivity and negative predictive value more than liver ultrasonography (83.3 vs. 77.8% and 98.4 vs. 98%, respectively); (2) in our series, we obtained a lower recurrence rate in classes A+B1 (7.5%) and B2 (20.8%) and higher in C1+C2 (44.4%) and D (66.7%) (p < 0.0 1).

CONCLUSION

According to these data we decided to eliminate postoperative liver ultrasonography and customize follow-up protocol on tumor staging and timing of cancer relapse. The authors believe that these changes will not modify the results, but cause less psychophysical stress for the patients and reduce costs by 50%.

摘要

背景

作者评估了接受根治性手术的结肠癌患者令人失望的随访结果后,尝试采用更合理的随访方式。

方法

在一项对约232例遵循随访方案患者的回顾性研究中,我们评估了癌胚抗原(CEA)、肝脏超声检查和腹部CT的准确率。在同一组患者中,我们评估了肿瘤复发率与阿斯特勒-科勒(Astler-Coller)分类之间的相关性类型。

结果

(1)在检测肝转移方面,CEA水平提供的敏感性和阴性预测值高于肝脏超声检查(分别为83.3%对77.8%和98.4%对98%);(2)在我们的系列研究中,A+B1期(7.5%)和B2期(20.8%)的复发率较低,C1+C2期(44.4%)和D期(66.7%)的复发率较高(p<0.01)。

结论

根据这些数据,我们决定取消术后肝脏超声检查,并根据肿瘤分期和癌症复发时间定制随访方案。作者认为,这些改变不会改变结果,但会减少患者的身心压力,并将成本降低50%。

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