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[大鼠伸肌腱部分和完全切断后愈合过程中胶原纤维的形态计量学研究]

[Morphometric study of collagen fibers during healing following partial and complete section of extensor tendons in rats].

作者信息

Chen Z, Hong G, Wan F

机构信息

Department of Hand Surgery, Union Hospital, Tongji Medical University, Wuhan, P.R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 1997 Sep;11(5):276-8.

PMID:9867928
Abstract

In order to study the influence of severity of tendon injury on the morphology of collagen fibers during healing process of extensor tendons, 40 female Wistal rats were used for investigation. The rats were divided into 2 groups. Transection of the tendon of extensor digitorum longus was performed in one group, while partial section of the same tendon was performed in the other group. Morphometric analysis was undertaken on the 15th, 30th, 60th and 90th day after operation. The result was that there was no significant difference between the two groups both in distribution and diameter of collagen fibers on the 15th and 30th days (P > 0.05). However, there was significent difference between those on the 60th and 90th days (P < 0.05). It was concluded that the severity of the tendon injury could influence the morphology of collagen fibers during the late stage of tendon healing.

摘要

为研究伸肌腱愈合过程中肌腱损伤严重程度对胶原纤维形态的影响,选取40只雌性Wistal大鼠进行研究。将大鼠分为2组。一组行趾长伸肌腱切断术,另一组行同一肌腱部分切断术。于术后第15、30、60和90天进行形态计量学分析。结果显示,术后第15天和30天,两组胶原纤维的分布和直径均无显著差异(P>0.05)。然而,术后第60天和90天两组之间存在显著差异(P<0.05)。结论是,肌腱损伤的严重程度可在肌腱愈合后期影响胶原纤维的形态。

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