Chen J, Hao X, Luo S
Department of Plastic Surgery, Honey Lake Hospital of Shenzen, P.R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 1997 Sep;11(5):286-90.
In order to investigate the survival mechanism and the role of venous drainage in arterialized venous skin flap, 60 rabbits' ears were used for research and clinical application of the flap was performed subsequently in two cases. The rabbits were divided into 4 groups. Experimental group was standard arterialized venous skin flap, control 1 group was venous skin flap, control 2 group was arterialized venous skin flap with only one drainage vein and control 3 group was normal skin flap. The process of survival of the flaps was observed by hemodynamic and histological method. The results showed that there was no significant difference between standard arterialized venous skin flap and normal skin flap (P > 0.01). Two cases of arterialized venous skin flap survived completely. The conclusion were as follow: 1. the opening of collateral circulation between the veinlets was the main change of the microcirculation; 2. the blood flow of the graft was changed from unphysiological circulation to physiological circulation as the time elapsed and 3. amelioration of venous drainage was important in inproving the survival rate of arterialized vein graft.
为了探讨动脉化静脉皮瓣的存活机制及静脉引流的作用，选用60只兔耳进行研究，随后对2例患者实施了该皮瓣的临床应用。将兔分为4组。实验组为标准动脉化静脉皮瓣，对照组1为静脉皮瓣，对照组2为仅有一条引流静脉的动脉化静脉皮瓣，对照组3为正常皮瓣。采用血流动力学和组织学方法观察皮瓣的存活过程。结果显示，标准动脉化静脉皮瓣与正常皮瓣之间无显著差异（P>0.01）。2例动脉化静脉皮瓣完全存活。结论如下：1. 微静脉之间侧支循环的开放是微循环的主要变化；2. 随着时间的推移，移植皮瓣的血流从非生理性循环转变为生理性循环；3. 改善静脉引流对提高动脉化静脉移植皮瓣的成活率至关重要。
