Sharma V K, Chandrashekaran M K, Singaravel M, Subbaraj R
Chronobiology Laboratory, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.
J Photochem Photobiol B. 1998 Sep;45(2-3):83-6. doi: 10.1016/s1011-1344(98)00152-3.
The circadian rhythm of locomotor activity in the nocturnal field mouse Mus booduga has been monitored after an exposure to ultraviolet-A (UV-A; wavelength between 350 and 400 nm) radiation at various hours of the subject's cycle. The magnitude of the phase shift is used to determine the sensitivity of the circadian pacemaker underlying locomotor activity rhythm. It is observed that UV-A shifts the phase of the locomotor activity rhythm in a phase-dependent manner. A phase response curve (PRC) is constructed to depict the time course and waveform of the basic oscillator's sensitivity to UV-A radiation. The UV-A PRC qualitatively resembles the PRC constructed using diffused daylight as stimulus. Furthermore, the phase response characteristics of the circadian pacemaker for UV-A suggest a periodically varying sensitivity to UV-A similar to that to daylight.
在夜间田鼠（Mus booduga）的活动周期的不同时间点暴露于紫外线A（UV-A；波长在350至400纳米之间）辐射后，对其运动活动的昼夜节律进行了监测。相移的幅度用于确定运动活动节律背后的昼夜节律起搏器的敏感性。观察到UV-A以相位依赖的方式改变运动活动节律的相位。构建了相位响应曲线（PRC）以描绘基本振荡器对UV-A辐射的敏感性的时间进程和波形。UV-A的PRC在定性上类似于使用漫射日光作为刺激构建的PRC。此外，昼夜节律起搏器对UV-A的相位响应特性表明，其对UV-A的敏感性与对日光的敏感性类似，呈周期性变化。
