接受结直肠癌手术患者性功能障碍的神经生理学评估
Neurophysiological evaluation of sexual dysfunction in patients operated for colorectal cancer.
作者信息
Pietrangeli A, Bove L, Innocenti P, Pace A, Tirelli C, Santoro E, Jandolo B
机构信息
Service of Neurology, Regina Elena Institute for Cancer Research, Rome, Italy.
出版信息
Clin Auton Res. 1998 Dec;8(6):353-7. doi: 10.1007/BF02309627.
Sexual dysfunction after colorectal cancer surgery may be severe and occurs in 25% to 100% of cases. Thirty-eight patients underwent colorectal resection; eight (21%) who were totally impotent and two (5%) who had ejaculatory failure were therefore studied to better understand the neurophysiological alterations related to this type of surgery. The patients were evaluated after surgery with electrophysiological testing, including examination of the sacral reflex (SR), pudendal somatosensory evoked potential (PEP), and motor evoked potential (MEP) responses. Sudomotor skin response (SSR) was also studied in a group of patients. Of the 38 patients studied, 29 showed abnormalities: six of SR, three of PEP, six of MEP, and fourteen of SSR. Only a combination of all these tests permits correct evaluation of the sexual dysfunction.
结直肠癌手术后的性功能障碍可能很严重，发生率在25%至100%之间。38例患者接受了结直肠切除术；因此，对8例（21%）完全阳痿和2例（5%）射精功能障碍的患者进行了研究，以更好地了解与这类手术相关的神经生理学改变。术后对患者进行了电生理测试评估，包括骶反射（SR）、阴部体感诱发电位（PEP）和运动诱发电位（MEP）反应检查。还对一组患者进行了汗腺运动皮肤反应（SSR）研究。在研究的38例患者中，29例出现异常：SR异常6例，PEP异常3例，MEP异常6例，SSR异常14例。只有综合所有这些测试才能正确评估性功能障碍。
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