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从西班牙咽拭子中分离出的914株β-溶血性链球菌的抗菌耐药性:一项为期1年(1996 - 1997年)的多中心监测研究结果。西班牙呼吸道病原体监测小组。

Antimicrobial resistance of 914 beta-hemolytic streptococci isolated from pharyngeal swabs in Spain: results of a 1-year (1996-1997) multicenter surveillance study. The Spanish Surveillance Group for Respiratory Pathogens.

作者信息

Baquero F, García-Rodríguez J A, de Lomas J G, Aguilar L

机构信息

Microbiology Department, Ramón y Cajal Hospital, Madrid, Spain.

出版信息

Antimicrob Agents Chemother. 1999 Jan;43(1):178-80. doi: 10.1128/AAC.43.1.178.

Abstract

A nationwide susceptibility surveillance study of beta-hemolytic streptococcal isolates from pharyngeal swabs obtained in 11 Spanish hospitals between May 1996 and April 1997 against 12 antibiotics was carried out. Of the isolates 86% (786 of 914 isolates) were group A and 8.4% (77 of 914 isolates) were group C. No resistance was found to beta-lactam antibiotics, but significant differences (P < 0.001) with respect to lack of susceptibility to macrolides were found between groups (27% for group A and 12% for group C) and between seasons (13.2% in summer and 31.7% in winter). Most of these isolates displayed the M phenotype (low-level resistance to erythromycin and susceptibility to clindamycin).

摘要

1996年5月至1997年4月期间,在西班牙11家医院对从咽拭子中分离出的β-溶血性链球菌进行了一项针对12种抗生素的全国性药敏监测研究。在分离出的菌株中,86%(914株中的786株)为A组,8.4%(914株中的77株)为C组。未发现对β-内酰胺类抗生素耐药,但在不同组(A组为27%,C组为12%)和不同季节(夏季为13.2%,冬季为31.7%)之间,发现对大环内酯类药物敏感性缺乏存在显著差异(P<0.001)。这些分离株大多表现为M表型(对红霉素低水平耐药,对克林霉素敏感)。

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