Shaheen F A, al-Sulaiman M H, Ramprasad K S, al-Khader A A
Saudi Center for Organ Transplantation, Riyadh, Saudi Arabia.
Ann Transplant. 1997;2(4):49-58.
One hundred and seventeen of 270 (43%) recipients of organs obtained from donors with malignancies had evidence of transmitted cancers. In 9 instances these were removed from renal allografts immediately prior to transplantation. Including these cases there were 45 recipients of organs in which a neoplasm involved the allograft, 6 others in whom adjacent structures were invaded, and another 66 patients who had distant metastases. Precautions to prevent cancer transmission include meticulous preoperative screening of donors, careful examination of all organs at the time of harvesting, biopsy of any suspicious lesions, and routine donor autopsy, if possible.
在270名接受来自患有恶性肿瘤的供体器官的受者中，有117名（43%）出现了移植传播癌症的证据。其中9例在移植前即刻从肾移植器官中切除。包括这些病例在内，有45名器官受者的肿瘤累及移植器官，6名受者的相邻结构受到侵犯，另有66名患者发生远处转移。预防癌症传播的措施包括术前对供体进行细致筛查、器官获取时仔细检查所有器官、对任何可疑病变进行活检以及尽可能进行常规供体尸检。
