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天然肺动脉瓣在体循环中的临床表现。

Clinical performance of the native pulmonary valve in the systemic circulation.

作者信息

Schmid F X, Hilker M, Kampmann C, Mayer E, Oelert H

机构信息

Department of Cardiovascular, Johannes Gutenberg-University, Mainz, Germany.

出版信息

J Heart Valve Dis. 1998 Nov;7(6):620-5.

PMID:9870195
Abstract

BACKGROUND AND AIM OF THE STUDY

In a number of corrective and palliative procedures the autologous pulmonary valve is used as the systemic semilunar valve. This study reviews the surgical results and function of the native pulmonary valve in the systemic position after various surgical procedures.

METHODS

Between January 1994 and December 1997, the autologous pulmonary valve was transferred functionally or anatomically into the systemic circulation in 89 patients. Follow up echocardiograms and cardiac angiograms were reviewed for 51 neonates with transposition of the great arteries after an arterial switch operation (ASO), in 21 patients after first-stage palliation of hypoplastic left heart syndrome (HLHS), in eight children and adults with pulmonary autograft aortic valve replacement (Ross procedure), and in nine patients with a pulmonary artery-to-aortic anastomosis (Damus-Kaye-Stansel (DKS) procedure) in complex heart defects with outflow obstruction.

RESULTS

Nine patients (five with HLHS) died; thus, overall mortality rate was 10.2%. There was no evidence of valve-related mortality. Trivial insufficiency following ASO was noted in 11 patients, with no progression of incompetence over time. None of the HLHS patients had pulmonary insufficiency preoperatively, but all showed mild regurgitation on postoperative echocardiography. There was a moderate increase in insufficiency which was attenuated after an early second-stage palliation. Three of nine patients undergoing a DKS anastomosis demonstrated a hemodynamically insignificant insufficiency. Modification of the surgical technique avoided postoperative regurgitation. Four of seven patients having a Ross procedure showed trivial but non-progressive neoaortic regurgitation.

CONCLUSIONS

Based on this experience, the autologous pulmonary valve performs adequately at intermediate term follow up. Postoperatively, trivial regurgitation was a frequent finding but was hemodynamically insignificant. Progression or late development of insufficiency as well as stenosis were rare problems.

摘要

研究背景与目的

在一些矫正和姑息性手术中,自体肺动脉瓣被用作体循环半月瓣。本研究回顾了各种外科手术后,天然肺动脉瓣在体循环位置的手术结果和功能。

方法

1994年1月至1997年12月期间,89例患者的自体肺动脉瓣通过功能或解剖方式转入体循环。对51例大动脉转位患儿在动脉调转术(ASO)后、21例左心发育不全综合征(HLHS)一期姑息术后、8例儿童及成人接受肺动脉自体移植主动脉瓣置换术(Ross手术)以及9例患有复杂心脏缺陷伴流出道梗阻行肺动脉-主动脉吻合术(Damus-Kaye-Stansel,DKS手术)的患者进行了随访超声心动图和心血管造影检查。

结果

9例患者(5例HLHS患者)死亡;因此,总死亡率为10.2%。没有瓣膜相关死亡的证据。ASO术后11例患者出现轻微反流,反流程度未随时间进展。HLHS患者术前均无肺动脉反流,但术后超声心动图均显示轻度反流。反流有中度增加,在早期二期姑息术后有所减轻。9例行DKS吻合术的患者中有3例显示血流动力学上无明显意义的反流。手术技术的改进避免了术后反流。7例接受Ross手术的患者中有4例出现轻微但无进展的新主动脉反流。

结论

基于这一经验,自体肺动脉瓣在中期随访中功能良好。术后轻微反流很常见,但血流动力学上无明显意义。反流进展或晚期出现以及狭窄是罕见问题。

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