Methotrexate-induced hepatic necrosis requiring liver transplantation in a patient with rheumatoid arthritis.
作者信息
Hakim N S, Kobienia B, Benedetti E, Bloomer J, Payne W D
机构信息
Department of Surgery, University of Minnesota, Minneapolis, USA.
出版信息
Int Surg. 1998 Jul-Sep;83(3):224-5.
PMID:9870779
Abstract
MTX-induced hepatic injury and liver enzyme elevations have been demonstrated after treatment of leukemia, gestational disease and during treatment of psoriasis and rheumatoid arthritis. A 40-year-old man with a long standing history of rheumatoid arthritis was treated with MTX over a 6 month period and developed an overwhelming hepatic necrosis. He was successfully transplanted.
摘要
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