Sun I C, Shen J K, Wang H K, Cosentino L M, Lee K H
Natural Products Laboratory, School of Pharmacy, University of North Carolina at Chapel Hill 27599-7360, USA.
Bioorg Med Chem Lett. 1998 May 19;8(10):1267-72. doi: 10.1016/s0960-894x(98)00202-9.
Eleven betulin derivatives were prepared and evaluated for anti-HIV activity in H9 lymphocytes. Compound 4 was found to be the most active with EC50 and TI values of 0.00066 microM and 21,515, respectively.
制备了11种桦木醇衍生物，并在H9淋巴细胞中评估其抗HIV活性。发现化合物4活性最高，其EC50和TI值分别为0.00066微摩尔和21515。
