从牙菌斑中分离出的表皮葡萄球菌细菌素的纯化及特性

Purification and properties of a bacteriocin of Staphylococcus epidermidis isolated from dental plaque.

作者信息

Nakamura T, Hirai K, Shibata Y, Fujimura S

机构信息

Department of Oral Microbiology, Matsumoto Dental University School of Dentistry, NAGANO-Ken, Japan.

出版信息

Oral Microbiol Immunol. 1998 Dec;13(6):387-9. doi: 10.1111/j.1399-302x.1998.tb00697.x.

DOI:10.1111/j.1399-302x.1998.tb00697.x

PMID:9872117

Abstract

An extracellular bacteriocin of Staphylococcus epidermidis isolated from dental plaque was purified and characterized. Its molecular mass was 3500 Da and pI was 10.5. This bacteriocin inhibited the growth of Staphylococcus aureus, Streptococcus salivarius, and Streptococcus mitis, but Streptococcus mutans, Streptococcus sanguis and other oral indigenous bacterial species examined were not inhibited. The mode of inhibition was found to be bacteriostatic.

摘要

从牙菌斑中分离出的表皮葡萄球菌胞外细菌素进行了纯化和特性鉴定。其分子量为3500 Da，等电点为10.5。这种细菌素可抑制金黄色葡萄球菌、唾液链球菌和缓症链球菌的生长，但对变形链球菌、血链球菌及其他检测的口腔固有细菌种类没有抑制作用。发现其抑制方式为抑菌。