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本文引用的文献

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Primary metabolite kinetics of bacteriocin biosynthesis by and evidence for stimulation of bacteriocin production under unfavourable growth conditions.[细菌名称]产生细菌素的初级代谢动力学以及在不利生长条件下刺激细菌素产生的证据。 （注：原文中“by ”后面缺少具体内容，这里根据语境补充了“[细菌名称]”，以便使译文更完整合理）
Microbiology (Reading). 1996 Apr;142(4):817-827. doi: 10.1099/00221287-142-4-817.
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Effect of compatible solutes on survival of lactic Acid bacteria subjected to drying.相容溶质对干燥乳酸菌存活的影响。
Appl Environ Microbiol. 1996 Jan;62(1):259-61. doi: 10.1128/aem.62.1.259-261.1996.
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Betaine Transport Imparts Osmotolerance on a Strain of Lactobacillus acidophilus.甘氨酸甜菜碱转运赋予嗜酸乳杆菌耐渗透压能力。
Appl Environ Microbiol. 1987 Oct;53(10):2275-81. doi: 10.1128/aem.53.10.2275-2281.1987.
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Physiological response of Lactobacillus plantarum to salt and nonelectrolyte stress.植物乳杆菌对盐和非电解质胁迫的生理反应。
J Bacteriol. 1998 Sep;180(17):4718-23. doi: 10.1128/JB.180.17.4718-4723.1998.
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Characterization of the lacticin 481 operon: the Lactococcus lactis genes lctF, lctE, and lctG encode a putative ABC transporter involved in bacteriocin immunity.乳酸乳球菌素481操纵子的特性：乳酸乳球菌基因lctF、lctE和lctG编码一种参与细菌素免疫的推定ABC转运蛋白。
Appl Environ Microbiol. 1997 Nov;63(11):4252-60. doi: 10.1128/aem.63.11.4252-4260.1997.
6
Lantibiotic nisin Z fermentative production by Lactococcus lactis IO-1: relationship between production of the lantibiotic and lactate and cell growth.乳酸乳球菌IO-1发酵生产羊毛硫抗生素乳链菌肽Z：羊毛硫抗生素的产生与乳酸及细胞生长之间的关系
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Osmotic regulation of intracellular solute pools in Lactobacillus plantarum.植物乳杆菌细胞内溶质池的渗透调节
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8
Choline transport activity in Staphylococcus aureus induced by osmotic stress and low phosphate concentrations.金黄色葡萄球菌中由渗透应激和低磷酸盐浓度诱导的胆碱转运活性。
J Bacteriol. 1993 Apr;175(8):2400-6. doi: 10.1128/jb.175.8.2400-2406.1993.
9
Characteristics and osmoregulatory roles of uptake systems for proline and glycine betaine in Lactococcus lactis.乳酸乳球菌中脯氨酸和甘氨酸甜菜碱摄取系统的特征及渗透调节作用
J Bacteriol. 1993 Sep;175(17):5438-44. doi: 10.1128/jb.175.17.5438-5444.1993.
10
Osmoregulation in Bacillus subtilis: synthesis of the osmoprotectant glycine betaine from exogenously provided choline.枯草芽孢杆菌中的渗透调节：从外源提供的胆碱合成渗透保护剂甘氨酸甜菜碱。
J Bacteriol. 1994 Sep;176(17):5364-71. doi: 10.1128/jb.176.17.5364-5371.1994.

渗透压和渗透保护剂的存在对乳酸乳球菌生长及细菌素产生的影响。

Influence of osmolarity and the presence of an osmoprotectant on lactococcus lactis growth and bacteriocin production.

作者信息

Uguen P, Hamelin J, Blanco C

机构信息

Laboratoire de Biologie et Chimie Moleculaires, Universite de Bretagne-Sud, 56000 Vannes, Universite de Rennes I, Campus de Beaulieu, 35042 Rennes, France.

出版信息

Appl Environ Microbiol. 1999 Jan;65(1):291-3. doi: 10.1128/AEM.65.1.291-293.1999.

DOI:10.1128/AEM.65.1.291-293.1999
PMID:9872793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC91016/
Abstract

Growth inhibition of Lactococcus lactis provoked by increasing osmolarity is reversed when glycine betaine (GB) or its analogs are added to a defined medium. Lacticin 481 production increased sharply with growth medium osmolarity in the absence of osmoprotectant but remained unaffected when GB was supplied in media of increasing osmolarity.

摘要

当向特定培养基中添加甘氨酸甜菜碱（GB）或其类似物时，渗透压升高所引发的乳酸乳球菌生长抑制作用会被逆转。在没有渗透压保护剂的情况下，乳酸链球菌素481的产量会随着生长培养基渗透压的升高而急剧增加，但当在渗透压不断升高的培养基中供应GB时，其产量不受影响。