Ross B, Lütkenhöner B, Pantev C, Hoke M
Institute of Experimental Audiology, University of Münster, Germany.
Audiol Neurootol. 1999 Jan-Feb;4(1):12-27. doi: 10.1159/000013816.
A method for the objective evaluation of the hearing threshold using cortical evoked response audiometry was developed. The method results in a kind of objective audiogram, visualizing the significance of an auditory evoked potential (AEP) in a scheme similar to a conventional audiogram. In the present implementation of the method, four frequencies are tested quasi-simultaneously (500, 1000, 2000 and 3000 Hz; intensity steps of 5 dB). The significance of an evoked potential is assessed by means of the Rayleigh test, which is applied to the phase values derived from certain time windows of the single-trial epochs. A retrospective analysis of 1, 920 threshold estimations in 240 subjects suggested that the detection threshold (lowest stimulus intensity yielding a significant response) was, on the average, 7.5 dB above the electrophysiological threshold (intensity where the AEP amplitude vanishes). The grand-average amplitude-intensity characteristic was approximated by the function a(1 - exp(-I/b)), with a = 6.25 microV, b = 22.3 dB and I representing the intensity (in decibels) relative to the electrophysiological threshold.
开发了一种使用皮层诱发反应测听法客观评估听力阈值的方法。该方法可得出一种客观听力图,以类似于传统听力图的方式呈现听觉诱发电位(AEP)的意义。在该方法的当前实施中,四个频率(500、1000、2000和3000赫兹;强度步长为5分贝)几乎同时进行测试。诱发电位的意义通过瑞利检验进行评估,该检验应用于从单次试验片段的特定时间窗口导出的相位值。对240名受试者的1920次阈值估计进行的回顾性分析表明,检测阈值(产生显著反应的最低刺激强度)平均比电生理阈值(AEP振幅消失时的强度)高7.5分贝。总体平均振幅-强度特征由函数a(1 - exp(-I/b))近似,其中a = 6.25微伏,b = 22.3分贝,I表示相对于电生理阈值的强度(以分贝为单位)。