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安蒂科拉纳山谷水对肾结石的体外溶剂效应:分析仪器研究

Solvent effect in vitro of Anticolana Valley water on renal stones: analytical-instrumental study.

作者信息

De Angelis Curtis S, Curini R, Fraioli A, Petronio B M, Ricciuti G, D'Ascenzo G

机构信息

Department of Chemistry, University of Rome La Sapienza, Rome (Italy).

出版信息

Nephron. 1999;81 Suppl 1:98-102. doi: 10.1159/000046305.

DOI:10.1159/000046305
PMID:9873221
Abstract

The presence of humic and fulvic acids in the Anticolana Valley (Fiuggi) water has been established. On the basis of this evidence we investigated the capacity of Anticolana Valley (Fiuggi) water to dissolve renal calculi in vitro. Crystals of calcium oxalate monohydrate to simulate a kidney stone were prepared. Human renal stones of calcium oxalate monohydrate were obtained by courtesy of the Division of Urology of 'La Sapienza' University (Rome), the Division of Urology of the University of Havana (Cuba) and the ASTIF of Fiuggi. The study was performed using the Anticolana Valley (Fiuggi) water, distilled water and tap water (ACEA, Rome), in a specially designed Perspex apparatus. Each calculus was subjected to a water flow of 2 liters/24 h. The capacity of the Anticolana Valley (Fiuggi) water to dissolve human and synthetic calculi was found to be much higher than that of distilled water which in turn was significantly more effective than tap (ACEA) water.

摘要

已证实安蒂科拉纳山谷(菲乌吉)的水中存在腐殖酸和富里酸。基于这一证据,我们研究了安蒂科拉纳山谷(菲乌吉)的水在体外溶解肾结石的能力。制备了一水合草酸钙晶体以模拟肾结石。一水合草酸钙的人体肾结石由罗马“萨皮恩扎”大学泌尿外科、哈瓦那大学(古巴)泌尿外科以及菲乌吉的ASTIF提供。该研究在一个特别设计的有机玻璃装置中,使用安蒂科拉纳山谷(菲乌吉)的水、蒸馏水和自来水(罗马阿西亚水务公司)进行。每颗结石都经受2升/24小时的水流。结果发现,安蒂科拉纳山谷(菲乌吉)的水溶解人体结石和人造结石的能力远高于蒸馏水,而蒸馏水又明显比自来水(罗马阿西亚水务公司)更有效。

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Solvent effect in vitro of Anticolana Valley water on renal stones: analytical-instrumental study.安蒂科拉纳山谷水对肾结石的体外溶剂效应:分析仪器研究
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