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膀胱肿瘤经尿道切除术后卡-梅综合征患者急性凝血病发作。

Acute onset of coagulopathy in a patient with Kasabach-Merritt syndrome following transurethral resection of bladder tumor.

作者信息

Shoji N, Nakada T, Sugano O, Suzuki H, Sasagawa I

机构信息

Department of Urology, Yamagata University School of Medicine, Yamagata, Japan.

出版信息

Urol Int. 1998;61(2):115-8. doi: 10.1159/000030300.

Abstract

We report an unusual case of Kasabach-Merritt syndrome in a 62 year-old woman with bladder tumor who suffered from acute consumption coagulopathy that increased the fibrinolytic activity due to the presence of a huge hemangioma in the upper and lower extremities. Two days after the transurethral resection of the solitary bladder tumor, serious hematuria and life-threatening disseminated intravascular coagulation developed. Following treatments with heparin and subsequent steroid treatment, hemorrhage and abnormal hemostatic values improved. It is suggested that extensive investigation of the coagulation system should be done in patients with giant hemangioma, particularly before a surgical procedure.

摘要

我们报告了一例罕见的卡萨巴赫-梅里特综合征病例,患者为一名62岁患有膀胱肿瘤的女性,因上下肢存在巨大血管瘤而出现急性消耗性凝血病,导致纤维蛋白溶解活性增加。在经尿道切除孤立性膀胱肿瘤两天后,出现了严重血尿和危及生命的弥散性血管内凝血。经过肝素治疗及随后的类固醇治疗后,出血情况及异常的止血指标有所改善。建议对患有巨大血管瘤的患者,尤其是在进行外科手术前,应全面检查凝血系统。

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