新型抗真菌剂的建模、合成及生物活性（1）
Modeling, synthesis and biological activity of novel antifungal agents (1).
作者信息
Tsukuda T, Shiratori Y, Watanabe M, Ontsuka H, Hattori K, Shirai M, Shimma N
机构信息
Department of Medicinal Chemistry, Nippon Roche Research Center, Kamakura, Japan.
出版信息
Bioorg Med Chem Lett. 1998 Jul 21;8(14):1819-24. doi: 10.1016/s0960-894x(98)00316-3.
PMID:9873440
Abstract
Homology modeling of candida lanosterol C-14 demethylase, synthesis and in vitro antifungal activities of cyclohexyl analogs of restricticin are described.
摘要
描述了念珠菌羊毛甾醇C-14脱甲基酶的同源建模、restricticin环己基类似物的合成及其体外抗真菌活性。
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