Câmpian E, Peterson M L, Saneii H H, Furka A
Advanced ChemTech Inc., Louisville, KY 40228, USA.
Bioorg Med Chem Lett. 1998 Sep 8;8(17):2357-62. doi: 10.1016/s0960-894x(98)00426-0.
Omission libraries, synthesized by omitting one amino acid in all coupling positions, are very efficient tools for the rapid identification of the amino acid components of bioactive peptides. Based on the determined amino acids, an occurrence library can be defined and prepared which is much less complex than the full one while still comprising the bioactive peptide.
缺失文库是通过在所有偶联位置省略一个氨基酸而合成的，是快速鉴定生物活性肽氨基酸组成的非常有效的工具。基于所确定的氨基酸，可以定义并制备一个出现文库，该文库比完整文库的复杂性要低得多，同时仍包含生物活性肽。
