Thalidomide analogs and PDE4 inhibition.
作者信息
Muller G W, Shire M G, Wong L M, Corral L G, Patterson R T, Chen Y, Stirling D I
机构信息
Celgene Corporation, Warren, NJ 07059 USA.
出版信息
Bioorg Med Chem Lett. 1998 Oct 6;8(19):2669-74. doi: 10.1016/s0960-894x(98)00475-2.
PMID:9873600
Abstract
N-Phthaloyl 3-amino-3-arylpropionic acid analogs of thalidomide that are potent inhibitors of tumor necrosis factor-alpha are reported. These compounds were found to be potent inhibitors of phosphodiesterase 4.
摘要
Zotero 插件