Riley J L, Robinson M E
The Claude Pepper Center for Research of Oral Health in Aging, College of Dentistry, University of Florida, Gainesville 32610, USA.
Clin J Pain. 1998 Dec;14(4):324-35. doi: 10.1097/00002508-199812000-00010.
To show clinical utility and empirical validity of Minnesota Multiphasic Personality Inventory-2 (MMPI-2) chronic pain patient subgroups by identification of differential multivariate relationships across groups.
This study used structural equation modeling to test cognitive coping strategies and somatization as mediator variables in path models with pain severity and depression used as exogenous (independent) variables and patient's activity level as the final endogenous (dependent) variable, across MMPI-2 profiles.
Hierarchical cluster analysis, performed on a sample of 569 chronic low back patients, resulted in four cluster profiles identifiable as those found in previous work with the MMPI-2 (within normal limits, V-type, neurotic triad, and depressed-pathological). Somatization mediated the relationship between depression and activity level for the neurotic triad group but not the other three groups. A positive linear relationship was found between somatization and depression for the within normal limits, neurotic triad, and depressed-pathological groups, whereas their linear association was negative for the V-type group. Cognitive coping strategies mediated the relationship between depression and activity level for the within normal limits group. In addition, cognitive coping was predictive of activity level for the within normal limits, V-type, and neurotic triad groups but not for the depressed-pathological group.
Consistent with previous cluster analytic studies, this study replicated four MMPI-2 cluster profile groups in chronic pain patients. These results have also shown that several multivariate relationships between variables are different across MMPI-2 groups, providing evidence for the validity for these MMPI-2 subgroups.
通过识别不同组间的多元差异关系,展示明尼苏达多相人格调查表第二版(MMPI - 2)慢性疼痛患者亚组的临床效用和实证效度。
本研究使用结构方程模型,以疼痛严重程度和抑郁作为外生(独立)变量,患者活动水平作为最终内生(依赖)变量,在MMPI - 2各剖面图中,检验认知应对策略和躯体化作为中介变量在路径模型中的作用。
对569例慢性下背痛患者样本进行分层聚类分析,得出四个聚类剖面图,与先前使用MMPI - 2的研究结果一致(正常范围、V型、神经症三联征和抑郁 - 病理型)。躯体化介导了神经症三联征组中抑郁与活动水平之间的关系,但在其他三组中未起到这种介导作用。在正常范围组、神经症三联征组和抑郁 - 病理型组中,躯体化与抑郁之间呈正线性关系,而在V型组中它们的线性关联为负。认知应对策略介导了正常范围组中抑郁与活动水平之间的关系。此外,认知应对可预测正常范围组、V型组和神经症三联征组的活动水平,但对抑郁 - 病理型组无此预测作用。
与先前的聚类分析研究一致,本研究在慢性疼痛患者中复制了四个MMPI - 2聚类剖面图组。这些结果还表明,不同MMPI - 2组之间变量的几个多元关系存在差异,为这些MMPI - 2亚组的效度提供了证据。