Korkmaz M E, Cekin A H
Int J Cardiol. 1998 Oct 30;66(3):317-8. doi: 10.1016/s0167-5273(98)00219-8.
In this report we describe an elderly lady, who after 27 days of ticlopidine treatment developed severe pancytopenia and gram (-) septicemia. No clinical response was obtained with an eight days course of empirical broad spectrum antibiotics, after which granulocyte colony stimulating factor (G-CSF, filgrastim) added to her regimen. In a period of seven days her neutrophil count was normal and she had recovered from septicemia. Twelve weeks after discharge she is fine and her blood parameters are all normal.
在本报告中，我们描述了一位老年女性，她在接受噻氯匹定治疗27天后出现了严重的全血细胞减少症和革兰氏阴性败血症。经验性使用广谱抗生素治疗8天未获得临床缓解，之后在她的治疗方案中加入了粒细胞集落刺激因子（G-CSF，非格司亭）。在7天的时间里，她的中性粒细胞计数恢复正常，败血症也已康复。出院12周后，她情况良好，血液参数均正常。
