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利用血管信息和一种新的模板技术进行脑植入物的治疗规划。

Treatment planning of brain implants using vascular information and a new template technique.

作者信息

De Bree J, Lagendijk J J, Raaymakers B W, Bakker C J, Hulshof M C, Koot R W, Hanlo P W, Struikmans H, Ramos L M, Battermann J J

机构信息

Department of Radiotherapy, University Hospital Utrecht, The Netherlands.

出版信息

IEEE Trans Med Imaging. 1998 Oct;17(5):729-36. doi: 10.1109/42.736026.

Abstract

A new template technique has been developed for implanting hyperthermia catheters in the treatment of brain tumors. The technique utilizes an imaging template and a drill template which can be rigidly secured to the head with three skull screws. The anatomic and vascular information needed for hyperthermia treatment planning may be assessed with three-dimensional magnetic resonance (MR) imaging and angiography acquisitions which use a surface coil. In the companioning treatment planning system the catheter positions and lengths and the electrodes in the catheter can be interactively manipulated relative to the anatomy and vasculature. The visualization of the blood vessels relative to the template allows the minimization of the risk on intracranial hemorrhages. This template technique is useful for any brain tumor implants, especially when a large number of catheters are involved. A phantom test has shown that this procedure has an accuracy in the order of 1 mm provided that the MR-related geometry distortions are minimized.

摘要

一种用于植入热疗导管治疗脑肿瘤的新模板技术已经研发出来。该技术利用一个成像模板和一个钻孔模板,它们可以通过三颗颅骨螺钉牢固地固定在头部。热疗治疗计划所需的解剖和血管信息可以通过使用表面线圈的三维磁共振(MR)成像和血管造影采集来评估。在配套的治疗计划系统中,导管的位置、长度以及导管中的电极可以相对于解剖结构和脉管系统进行交互式操作。相对于模板的血管可视化能够将颅内出血的风险降至最低。这种模板技术对任何脑肿瘤植入都很有用,尤其是在涉及大量导管的情况下。一个模型测试表明,只要将与MR相关的几何畸变降至最低,该程序的精度可达1毫米左右。

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