Sparacia G, Banco A, Midiri M, Iaia A
Institute of Radiology P. Cignolini, University of Palermo, Italy.
AJNR Am J Neuroradiol. 1998 Nov-Dec;19(10):1905-7.
To identify the optimal MR imaging technique for diagnosing pituitary iron overload, we compared spin-echo and gradient-echo MR imaging with measurements of pituitary T2 relaxation times in 30 patients with secondary hemochromatosis due to transfusion-dependent beta-thalassemia major and in 10 healthy volunteers. We found that the optimal MR imaging technique to evaluate pituitary iron overload is the gradient-echo T2*-weighted technique, as it best demonstrated signal reduction in the anterior lobe of the pituitary gland.
为了确定诊断垂体铁过载的最佳磁共振成像（MR）技术，我们对30例因重型输血依赖型β地中海贫血导致继发性血色素沉着症的患者以及10名健康志愿者，采用自旋回波和梯度回波MR成像技术并测量垂体T2弛豫时间进行了比较。我们发现，评估垂体铁过载的最佳MR成像技术是梯度回波T2*加权技术，因为它能最清晰地显示垂体前叶的信号降低。
