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Commentary: A revised view of local anesthetic action: what channel state is really stabilized?

作者信息

Scheuer T

机构信息

University of Washington, Seattle, Washington 98195-7280, USA.

出版信息

J Gen Physiol. 1999 Jan;113(1):3-6. doi: 10.1085/jgp.113.1.3.

DOI:10.1085/jgp.113.1.3
PMID:9874683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2222995/
Abstract
摘要

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本文引用的文献

1
Effects of calcium ions and local anesthetics on electrical properties of Purkinje fibres.钙离子和局部麻醉药对浦肯野纤维电特性的影响。
J Physiol. 1955 Sep 28;129(3):568-82. doi: 10.1113/jphysiol.1955.sp005379.
2
The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels.利多卡因阻断电压门控性Na+通道期间快速失活门的位置。
J Gen Physiol. 1999 Jan;113(1):7-16. doi: 10.1085/jgp.113.1.7.
3
Slow inactivation does not affect movement of the fast inactivation gate in voltage-gated Na+ channels.缓慢失活并不影响电压门控钠通道中快速失活门的移动。
J Gen Physiol. 1998 Jan;111(1):83-93. doi: 10.1085/jgp.111.1.83.
4
Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels.局部麻醉药作为变构门控的效应剂。利多卡因对失活缺陷型大鼠骨骼肌钠通道的影响。
J Clin Invest. 1996 Dec 15;98(12):2874-86. doi: 10.1172/JCI119116.
5
Movement of the Na+ channel inactivation gate during inactivation.失活过程中Na⁺通道失活门的运动。
J Biol Chem. 1996 Nov 29;271(48):30971-9. doi: 10.1074/jbc.271.48.30971.
6
Na+ channels must deactivate to recover from inactivation.钠离子通道必须失活才能从失活状态恢复。
Neuron. 1994 Apr;12(4):819-29. doi: 10.1016/0896-6273(94)90335-2.
7
On the molecular nature of the lidocaine receptor of cardiac Na+ channels. Modification of block by alterations in the alpha-subunit III-IV interdomain.关于心脏钠通道利多卡因受体的分子本质。通过α亚基III-IV结构域间的改变对阻滞作用的修饰。
Circ Res. 1995 Sep;77(3):584-92. doi: 10.1161/01.res.77.3.584.
8
Lidocaine block of cardiac sodium channels.利多卡因对心脏钠通道的阻滞作用。
J Gen Physiol. 1983 May;81(5):613-42. doi: 10.1085/jgp.81.5.613.
9
Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs.抗心律失常药物：钠通道阻滞剂和钙通道阻滞剂的受体调节作用机制
Annu Rev Pharmacol Toxicol. 1984;24:387-423. doi: 10.1146/annurev.pa.24.040184.002131.
10
Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons.乌贼轴突中季铵离子注入引起的钾离子电导失活及相关现象。
J Gen Physiol. 1969 Nov;54(5):553-75. doi: 10.1085/jgp.54.5.553.