Ikeda Y
Nihon Heikatsukin Gakkai Zasshi. 1976 Jun;12(2):87-95. doi: 10.1540/jsmr1965.12.87.
Twelve adult dogs fasted over night were used under Nembutal anesthesia. The intragastric pressure was measured by strain-gauge method with open tip cannula via duodenum. The stomach was filled through the cannula with 50 ml of Ringer's solution in a stepwise manner every two minutes until a total of 600 ml. Following results were obtained: 1) The intragastric pressure was more elevated on the vagotomized and the splanchnicotomized dogs than on the intact animals by a stepwise augmentation of Ringer's solution. 2) On the animals which were transected totally the extrinsic nerves, the increase of the intragastric pressure was the most. 3) It may be concluded that the elevation of intragastric pressure after denervation of the extrinsic nerves, due to the abolitions of vagal and splanchnic inhibitory reflexes.
选用12只成年犬,戊巴比妥钠麻醉,禁食过夜。采用应变片法,通过十二指肠开放尖端套管测量胃内压。经套管每两分钟逐步向胃内注入50ml林格氏液,直至总量达600ml。得到以下结果:1)随着林格氏液逐步注入,迷走神经切断和内脏神经切断的犬胃内压升高幅度大于正常犬。2)完全切断外在神经的动物,胃内压升高幅度最大。3)可以得出结论,外在神经去神经后胃内压升高是由于迷走神经和内脏抑制反射消失所致。