Messiaen T, Cosyns J P, Ferrant A, Jadoul M
Department of Nephrology, Cliniques Universitaires St. Luc, University of Louvain Medical School, Brussels, Belgium.
Clin Nephrol. 1998 Dec;50(6):387-9.
The authors report a case of necrotizing glomerulonephritis, with granular immune deposits, leading to the etiologic diagnosis of splenic non-Hodgkin's Lymphoma (NHL). The serum creatinine, initially markedly elevated, decreased under steroids and chlorambucil. Unfortunately, the patient died from septic complications. The importance of a careful search for a (localized) NHL in case of necrotizing glomerulonephritis with granular immune deposits is emphasized.
作者报告了一例坏死性肾小球肾炎病例，伴有颗粒状免疫沉积物，最终病因诊断为脾脏非霍奇金淋巴瘤（NHL）。血清肌酐最初显著升高，在使用类固醇和苯丁酸氮芥后下降。不幸的是，患者死于败血症并发症。强调了在出现伴有颗粒状免疫沉积物的坏死性肾小球肾炎时仔细寻找（局限性）NHL的重要性。
